Dry lab as a service:
xyna.bio
We are a Contract Research Organization specialized on in-silico engineering and screening of therapeutic agent systems with a strong focus on VHH based drug conjugates.
hybrid modeling ○ AI orchestration ○ closed-loop systems ○ virtual screening
Our Vision
We envision a future where VHHs, NDCs, and multifunctional biologic systems can be engineered through continuous interaction between simulation, AI-driven modeling, and experimental validation.
Our goal is to establish intelligent engineering workflows that bridge dry lab and wet lab to enable scalable development of highly targeted biologic therapeutics.
Model, simulate and optimize complex molecular systems before they enter the lab
VHHs and VHH-based conjugates are enabling a new class of targeted therapeutics with highly specialized functionality.
To fully realize their potential, these systems must be understood not only at the molecular level, but as dynamic functional entities with complex structural and biophysical behaviour
xyna.bio combines simulation, modeling, and human-guided computational workflows to support the in-silico design of these systems before they are validated in the lab.
Our Mission
Supporting our clients in accelerating the design of VHH-based therapeutics through advanced in-silico engineering workflows.
- Tailored data pipelines built to your specific workflows
- Request custom analytics tools
- Optimized for batch processing and high-throughput performance
- Reliable, secure data handling
- Priority support and direct collaboration with our technical team
Publications & Case Studies
Video
Design More Stable Nanobodies: Full Walkthrough of xyna.bio’s Aggregation Pipeline
Watch our walkthrough video for the Nanobody Aggregation Score Pipeline!
In this demo, we show how to predict VHH aggregation risk using our pipeline developed together with Prof. Dr. Harald Kolmar’s group at TU Darmstadt and Felix Geyer.
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Play VideoBreaking News:
xyna.bio @ BIO International Convention 2026
What we took away from #BIO2026 in San Diego: strong science, real manufacturing needs, and a maturing view on AI. A few themes clearly stood out: ADCs, conjugates, and lipid-based drug delivery were among the hottest topics, while lab automation continues to gain momentum. Antibodies remain the dominant biologics language, but VHHs deserve a much stronger position in that conversation and take up more and more space. One of the most valuable takeaways for us was the quality of conversations around AI. We saw strong interest in our neuro-physical approach, especially from teams looking for more intelligent modelling, triage, and design support. At the same time, there is understandable caution. Many companies have already had mixed experiences with AI-based discovery: faster processes, but not always better candidates. The message was clear: AI needs to deliver quality, not just speed. For xyna.bio, this reinforces why trust, scientific grounding, and VHH-specific expertise matter. Within the broader GIP Exyr GmbH and Xyna ecosystem, this principle is already reflected in initiatives such as the Catalyst project by xyna.com on trusted agentic AI for access and permissions management, where transparency, explainability, auditability, and clear governance boundaries are central. We see the same need in biotech: the opportunity is not to use AI as a label, but to build reliable & trusted, domain-specific tools that support better biological decision-making. Thank you to everyone we met in San Diego. We are excited to keep the conversations going.
Read moreFriday, July 3, 2026More latest articles:
Cooperation with AG Kronberger @Eberhard-Karls Universität Tübingen
We’re excited to announce an upcoming collaboration between xyna.bio and AG Kronberger at Universitätsmedizin Eberhard-Karls Universität Tübingen.This partnership aims to explore new frontiers in VHH engineering:A central goal of the collaboration is to build an AI system that can dramatically accelerate molecular simulations for VHHs. This would allow VHH and conjugates and their interactions to be modeled and analyzed much faster than with traditional computational methodsWe believe that integrating advanced AI with deep scientific expertise will open powerful new possibilities for drug discovery and precision therapeutics.Looking forward to what we will build together
Read moreWednesday, May 13, 2026xyna.bio is a sponsor for BFH
Three times - always a charm!We are proud to announce that xyna.bio is a sponsor of the BFH European Meet-Up for a third time this year.It is impressive to see how early collaboration shapes success in later stages of the competition, and we look forward to engaging with the next generation of innovators.
Read moreTuesday, April 14, 2026San Diego, here we come!
🚀 Heading to BIO International Convention 2026? Let’s connect.We’ll be using the BIO Partnering™ system to connect with innovators across the global biotech ecosystem.At xyna.bio, we’re addressing one of the key challenges in protein engineering and biologics discovery: reducing design uncertainty. Our AI-enabled hybrid modeling approach combines machine learning, physics-based simulation, and expert knowledge to deliver decision-ready insights across the full in silico workflow.We are especially focused on: → VHH / nanobody-based discovery and engineering → VHH-drug conjugates → In silico screening and experimental design acceleration → VHH applications for diagnostics and therapeutic innovationIf you're attending BIO 2026, feel free to reach out via the BIO Partnering™ platform. We’d love to explore how we can collaborate.
Read moreThursday, April 2, 2026Follow us on Social Media
Connection beyond platforms
Community-driven innovation is at the heart of xyna.bio. We shape goals and requirements together with you, ensuring that our platform evolves to meet real research needs. So become part of the xyna.bio community! Follow us on social media for the latest updates, insights, and discussions on the future of computational bioscience.
Disclaimer
Use of xyna.bio is intended for research purposes only and not for clinical decision-making. All in silico results, regardless of how obtained, must be experimentally validated. xyna.bio must not be used for the design, development, or facilitation of biological weapons, harmful biological agents, or any illegal, terrorist, or malicious activities.